Nisoxetine hydrochloride 是一种有效的和选择性的去甲肾上腺素转运蛋白 (NET) 抑制剂,Kd 值为 0.76 nM。Nisoxetine hydrochloride 是一种抗抑郁试剂和局部麻药,它可以阻断电压门控性钠通道。 Product description: Nisoxetine hydrochloride is a potent and selective inhibitor of noradrenaline transporter (NET), with a Kd of 0.76 nM. Nisoxetine hydrochloride is an antidepressant and local anesthetic, it can block voltage-gated sodium channels. Application: Nisoxetine has been used as a norepinephrine transport (NET) blocker in autoradiography studies. It has also been used as a NET blocker to study its effects on perivascular adipose tissue.
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Nisoxetine hydrochloride
CAS number:57754-86-6 molecular formula:C17H21NO2.HCl
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| Chinese alias | (±)-γ-(2-甲氧基苯氧基)-N-甲基苯丙胺盐酸盐' | ||
| English alias | AC-36596 | Q27273347 | N-151 | SR-01000075280 | CAS-14929-11-4 | 4-((2-NITROPHENYL)THIO)-2H-OXETE HCL | (+/-)-?-(2-Methoxyphenoxy)-N-methylbenzenepropanamine hydrochloride | SMR000326908 | UNII-9X76P2Y0EM | SR-01000075280-6 | NCGC00261586-01 | Nisoxetine | ||
| CAS number | 57754-86-6 | molecular formula | C17H21NO2.HCl |
| molecular weight | 307.82 g/mol | Exact mass | ≥99% |
| PSA | 30.500 Ų | logp | - |
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