compound introduction
产品应用： 在电流钳记录期间，美卡拉明盐酸盐已被用作细胞外盐水中的添加剂以减少突触输入。它还被用作主动脉体神经元和 MLO-Y4 细胞中的非选择性烟碱乙酰胆碱受体阻断剂。 Mecamylamine Hydrochloride is a noncompetitive and nonselective antagonist of AChRs. The compound preferentially blocks nicotinic receptors at autonomic ganglia and is able to cross the blood brain barrier. Once across the blood brain barrier Mecamylamine Hydrochloride can selectively antagonize neuronal AChRs. Mecamylamine Hydrochloride is an inhibitor of AChR α 3, AChR α 4, AChR α 7 and AChRβ2. A noncompetitive nicotinic AChR inhibitor.
