用于制备多种大环内酯类天然产物的多功能内酯化试剂。 介绍： 2-甲基-6-硝基苯甲酸酐可用作酰胺、内酯、酯和肽合成中的偶联促进剂 用途： 2-甲基-6-硝基苯甲酸酐可用于： 作为多功能的内酯化试剂用于制备各种大环内酯天然产物和内酯。 作为反应促进剂采用相应的胺和羧酸合成羧酰胺衍生物。 GRP78 抑制剂 prunustatin A、抗真菌化合物 (3R,16E,20E,23R)-(−)-eushearilide 和防肥胖药四氢利泼斯汀的全合成。 A versatile lactonization reagent used in the preparation of a variety of macrolide natural products. product description： 2-Methyl-6-nitrobenzoic anhydride is a reagent employed as a coupling promoter in the synthesis of amides, lactones, esters, and peptides. application： 2-Methyl-6-nitrobenzoic anhydride can be used: As a versatile lactonization reagent applicable in the preparation of varieties of macrolide natural products and lactones. As a reaction promoter in the synthesis of carboxamide derivatives by using corresponding amines and carboxylic acids. In the total synthesis of GRP78 inhibitor prunustatin A, antifungal compound (3R,16E,20E,23R)-(−)-eushearilide and an antiobestic drug tetrahydrolipstatin.
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2-Methyl-6-nitrobenzoic anhydride
Dangerous GoodsCAS number：434935-69-0 molecular formula：C16H12N2O7
overview
compound introduction
Specs
| Chinese alias | 6-硝基邻甲苯酸酐 | ||
| English alias | M1439 | 2-methyl-6-nitrobenzoic acid [(2-methyl-6-nitrophenyl)-oxomethyl] ester | FT-0658534 | EC8MK6FE8B | DS-18220 | UNII-EC8MK6FE8B | YEKPNMQQSPHKBP-UHFFFAOYSA-N | SCHEMBL329162 | (2-methyl-6-nitro-phenyl)carbonyl 2-methyl-6-nitro-benzoate | 2-Methyl-6 | ||
| CAS number | 434935-69-0 | molecular formula | C16H12N2O7 |
| molecular weight | 344.28 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 135.000 Ų | logp | 3.600 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US)， Eyeshields， Gloves
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
434935-69-0 | 2-Methyl-6-nitrobenzoic anhydride.pdf
