Palladium-catalyzed carbonylation of iodoanilines provides ketoamides in the presence of primary and secondary amines.在伯胺和仲胺存在的条件下，碘苯胺可经钯催化发生羰基化反应，生成酮酰胺 Palladium-catalyzed carbonylation of iodoanilines provides ketoamides in the presence of primary and secondary amines. Reactant involved in: 1.Hydroamination-double hydroarylation for synthesis of fuzed carbazoles. 2. Cycloisomerizations of aromatic homo- and bis-homopropargylic amine / amide intermediates. 3.Asymmetric organocatalytic condensation and cycloaddition. 4. Regioselective aryl C-H bond functionalization. 5.Synthesis of [(triisopropylsilyl)ethynyl]indole derivatives. 6.Domino condensation / S-arylation / heterocyclization reactions. 7.Palladium-catalyzed carbonylation of iodoanilines provides ketoamides in the presence of primary and secondary amines.
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4-Amino-3-iodobenzonitrile
Dangerous GoodsCAS number：33348-34-4 molecular formula：C7H5IN2
overview
compound introduction
Specs
| Chinese alias | 4-氨基-3-碘苯甲腈 | 4-氰基-2-碘苯胺 | ||
| English alias | Benzonitrile, 4-amino-3-iodo- | 4-Cyano-2-iodoaniline | MFCD04039964 | SCHEMBL98131 | 4-cyano-6-iodoaniline | J-019157 | AM61462 | DTXSID90403041 | EN300-104430 | FT-0647066 | SY023677 | DS-2278 | AKOS015889706 | 4-Amino-3-iodobenzonitrile, 98% | UOWVTQFT | ||
| CAS number | 33348-34-4 | molecular formula | C7H5IN2 |
| molecular weight | 244.03 g/mol | Exact mass | ≥98% |
| PSA | 49.800 Ų | logp | 1.600 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US), Eyeshields, Gloves
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
33348-34-4 | 4-Amino-3-iodobenzonitrile.pdf
