Ch55 是一种有效的合成类维生素 A。Ch55 与 RAR-α 和 RAR-β 受体具有高亲和力。Ch55 对细胞视黄酸结合蛋白 (CRABP) 的亲和力较低。Ch55 是 HL60 细胞分化的有效诱导物,EC50 为 200 nM,可用于癌症的研究。
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Ch 55
CAS number:110368-33-7 molecular formula:C24H28O3
overview
compound introduction
Specs
| Chinese alias | 4-[((1E)-3-[3,5-双(1,1-二甲基乙基)苯基] -3-氧代-1-丙烯基]苯甲酸 | ||
| English alias | SCHEMBL2307737 | Benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)- | 4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxo-prop-1-enyl]benzoic acid | 4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid | CH55 | Ch-55 | J-002418 | HMS3 | ||
| CAS number | 110368-33-7 | molecular formula | C24H28O3 |
| molecular weight | 364.47 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 54.400 Ų | logp | 6.600 |
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