Chlorhexidine, Dihydrochloride is an anti-microbial agent that acts as an inhibitor of MMP-2 and MMP-9 metalloproteinases. However, MMP-2 is more sensitive to chlorhexidine than MMP-9. Chlorhexidine dihydrochloride inhibits the collagenase activity of MMP-8 released by PMA-triggered polymorphonuclear leukocytes (PMNs) in a dose-dependent manner. Chlorhexidine dihydrochloride may possibly act through a cation-chelating mechanism. Chlorhexidine, Dihydrochloride is an anti-microbial agent that acts as an inhibitor of MMP-2 and MMP-9 metalloproteinases. However, MMP-2 is more sensitive to chlorhexidine than MMP-9. Chlorhexidine dihydrochloride inhibits the collagenase activity of MMP-8 released by PMA-triggered polymorphonuclear leukocytes (PMNs) in a dose-dependent manner. Chlorhexidine dihydrochloride may possibly act through a cation-chelating mechanism.
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Chlorhexidine dihydrochloride
Dangerous GoodsCAS number：3697-42-5 molecular formula：C22H30Cl2N10·2HCl
overview
compound introduction
Specs
| Chinese alias | 氯己定二盐酸盐 | ||
| English alias | CHLORHEXIDINE DIHYDROCHLORIDE (EP MONOGRAPH) | Chlorhexidine dihydrochloride, European Pharmacopoeia (EP) Reference Standard | Chlorhexidine HCl | 1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide) dihydrochloride | NSC 756679 | CHLORHEXIDINE HYDROCHLORID | ||
| CAS number | 3697-42-5 | molecular formula | C22H30Cl2N10·2HCl |
| molecular weight | 578.37 g/mol | Exact mass | 10mM in DMSO |
| PSA | 178.000 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08 , GHS09 , GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H373: 通过长时间或反复暴露对器官造成损害 H411: 对水生生物有毒并具有长期持续影响 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US),Eyeshields,Gloves
RTECS：
XA5285000
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
3697-42-5 | Chlorhexidine dihydrochloride.pdf
