compound introduction
医药中间体。是许多半合成头孢菌素的起始原料。各种半合成头孢菌素的工业生产，是由发酵制得头孢菌素C。再用化学裂解获得母核7-ACA，然后进行化学改造的途径制取的。 产品应用 细菌（金黄色葡萄球菌）β-内酰胺酶的有效抑制剂。 Product Application 7-Aminocephalosporanic acid (7-ACA) can be used as a starting material to synthesize: Cefotaxime by acylation reaction with S-benzothiazol-2-yl(2-amino-4-thiazolyl)(methoxyimino)thioacetate (MAEM) in the presence of triethylamine. Cefpodoxime proxetil, a third-generation antibiotic via cefotaxime intermediate. Sodium 3′-substituted cephalosporanate sulfone derivatives as potential inhibitors of β-lactamase.
