Benzyl carbazate is used as a reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method. It is also used in the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation.
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Benzyl carbazate
Dangerous GoodsCAS number:5331-43-1 molecular formula:C8H10N2O2
overview
compound introduction
Specs
| Chinese alias | 肼基甲酸苄酯 | 肼羧酸苯甲酯 | 苄基肼基甲酸酯 | 苄氧基甲酰肼 | 苄氧羰基肼 | N-Cbz-肼 | ||
| English alias | (benzyloxy)carbohydrazide | 4-[(2,4-dihydroxyphenyl)diazenyl]-3-hydroxynaphthalene-1-sulfonic acid | Phenylmethyl hydrazinecarboxylate | Carbobenzoxyhydrazine | Hydrazine, n-cbz protected | Benzyl hydrazinocarboxylate | 5-Amino-4-cyanopyrazole | Benzyl hy | ||
| CAS number | 5331-43-1 | molecular formula | C8H10N2O2 |
| molecular weight | 166.18 g/mol | Exact mass | ≥98% |
| PSA | 64.400 Ų | logp | 0.900 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS05
Signal word:
Danger
Hazard Statement:
H319: 引起严重眼睛刺激 H302: 吞食有害 H318: 造成严重的眼睛损伤 H372: 通过长时间或反复暴露对器官造成损害
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽:请寻求医疗帮助。 P305+P354+P
WGK Germany:
3
Personal protective equipment:
dust mask type N95 (US),Eyeshields,Gloves
RTECS:
MV1724950
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
5331-43-1 | Benzyl carbazate.pdf





