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Clozapine

Dangerous Goods

CAS number：5786-21-0    molecular formula：C18H19ClN4

overview
Specs
numbering system
physicochemical properties
Safety information
Production methods and uses
Related
MSDS
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overview

compound introduction

Clozapine 是一种有效的5-HT1C受体拮抗剂，作用于5-HT刺激的磷酸肌醇水解，IC50为110 nM。 Selective antagonist for D4-dopamine receptor. Antagonist at 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 serotonin receptors. Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. Selective antagonist for D4-dopamine receptor. Antagonist at 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 serotonin receptors.

Specs

Chinese alias8-氯-11-(4-甲基-1-哌嗪基)-5H-二苯并[b,e][1,4]-二氮杂草
English aliasClozapine (JAN/USP/INN) | HSDB 6478 | Prestwick1_000350 | Clozapine (Clozaril) | Clozapina [INN-Spanish] | KBio2_005446 | W-801 | 3-chlorophenylboronic acid;3-CHLOROPHENYL BORONIC ACID | 4-(methylsulphonyl)-benzeneboronic acid | 8-Chloro-11-(4-methyl-1-pi
CAS number5786-21-0molecular formulaC18H19ClN4
molecular weight326.82 g/molExact mass-
PSA30.900 Ųlogp3.1

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：
GHS06 , GHS08
Signal word：
Danger
Hazard Statement：
H301: 吞咽会中毒 H341: 怀疑引起遗传缺陷 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P281: 根据需要使用个人防护设备。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P203: 使用前，获取、阅读并遵守所有安全说明。 P301+P316: 如果吞咽：立即寻求紧急医疗救助。 P318: 如果暴露或担心，请就医。
WGK Germany：
3
RTECS：
HP1750000

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
5786-21-0 | Clozapine for peak identification.pdf