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6-Mercaptopurine monohydrate

Dangerous Goods

CAS number:6112-76-1    molecular formula:C5H4N4S·H2O

overview

compound introduction

不溶于水,溶于稀碱溶液,微溶于稀硫酸,溶于热乙醇,不溶于丙酮和醚。6 -巯基嘌呤,是一种广泛使用的抗白血病剂.可阻断次黄嘌呤转变为腺嘌呤核苷酸及鸟嘌呤核苷酸而抑制核酸的合成,对多种肿瘤均有抑制作用。主要作用于细胞周期的S期。 6-Mercaptopurine is a widely used antileukemic agent that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

Specs

Chinese alias6-嘌呤硫醇
English alias6,7-dihydro-3H-purine-6-thione hydrate | M-2690 | MERCAPTOPURINE [WHO-DD] | HMS2233O12 | MERCAPTOPURINE HYDRATE [JAN] | Q27114691 | 6-Mercaptopurine (6-MP) Monohydrate | 7H-purine-6-thiol hydrate | MERCAPTOPURINE [ORANGE BOOK] | Mercaptopurine, British Ph
CAS number6112-76-1molecular formulaC5H4N4S·H2O
molecular weight170.19 g/molExact mass≥99.5%
PSA86.200 Ųlogp-

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS07
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
WGK Germany:
3
Personal protective equipment:
dust mask type N95 (US),Eyeshields,Gloves
RTECS:
UP0400000
UN Number:
2811
Packing Group:

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
6112-76-1 | 6-Mercaptopurine monohydrate.pdf