产品用途： 2-溴苯甲醛的合成应用 包括： 通过铜催化的级联反应合成氮杂稠合多环喹啉。 CuI 催化偶联N-芳基肼合成1-取代吲唑。 它是抗癌药物 (-)-紫杉醇全合成中的关键起始原料。 钯/铜催化的 2-溴苯甲醛和不饱和亚胺衍生的末端乙炔的偶联和环化反应可用于合成广泛的异喹啉，包括十苯胺B。 芴-9-酮可在钯 (0) 催化剂存在下，由 2-（三甲基硅烷基）芳基三氟甲磺酸酯与 2-溴苯甲醛原位生成炔环合成。 它也可用于构建多种甾体骨架，其中环 A 来源于 2-溴苯甲醛。 Synthetic applications of 2-bromobenzaldehyde include: Synthesis of aza-fused polycyclic quinolines through copper-catalyzed cascade reaction. Preparation of 1-substituted indazoles by CuI-catalyzed coupling with N-aryl hydrazides. It is a key starting material in the total synthesis of an anticancer agent, (-)-taxol. Palladium/copper-catalyzed coupling and cyclization of terminal acetylenes derived from 2-bromobenzaldehyde and unsaturated imines can be used in the synthesis of wide range of isoquinolines, including decumbenine B. Fluoren-9-ones can be synthesized by annulation of arynes, generated in situ from 2-(trimethylsilyl)aryl triflates, with 2-bromobenzaldehyde in the presence of palladium(0) catalyst. It can also be used to build a variety of steroid frameworks, in which ring A is derived from 2-bromobenzaldehyde.
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2-Bromobenzaldehyde
Dangerous GoodsCAS number：6630-33-7 molecular formula：C7H5BrO
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | AKOS000120460 | PS-8508 | 2-Formylbromobenzene | bromo benzaldehyde | FT-0623222 | ortho-Bromobenzaldehyde | 2-brombenzaldehyde | 2-Bromobenzaldehyde, 98% | Q33859440 | B0836 | EN300-20472 | NSC60390 | NSC-60390 | S-Methyl GSH | NSC 60390 | EINECS 229-622 | ||
| CAS number | 6630-33-7 | molecular formula | C7H5BrO |
| molecular weight | 185.02 g/mol | Exact mass | ≥98% |
| PSA | 17.100 Ų | logp | 2.4 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
3
Personal protective equipment：
Eyeshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
6630-33-7 | 2-Bromobenzaldehyde.pdf
