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D-Glutamic acid

Dangerous Goods

CAS number:6893-26-1    molecular formula:C5H9NO4

overview

compound introduction

谷氨酸的非天然异构体。水中溶解度:7 g/L (20°C),实际上不溶于有机溶剂。D-谷氨酸适用于GR酶(谷氨酸消旋酶)及其抑制剂的结构亲和关系(SAR)研究。 D-谷氨酸是细菌肽聚糖结构的必需成分。可通过D-谷氨酸添加酶(murD)将其加入UDP-N-乙酰胞壁酰-L-丙氨酸(UDP-MurNAc-L-丙氨酸)中。然后将其掺入肽聚糖前体中。 肽聚糖构成革兰氏阳性和阴性细菌的细胞壁。通过谷氨酸消旋酶(GR)将L-谷氨酸转化为D-谷氨酸是肽聚糖合成中必不可少的步骤。 D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan. application: D-Glutamic acid acts as a superior to alpha ketoglutarate. It helps in the growth of Lactobacillus arabinosus. It can inhibit the IgE binding to peanut allergens. It is widely used in pharmaceuticals and foods.

Specs

Chinese aliasD-麸氨酸 | (R)-2-氨基戊二酸 | R-(-)-1-氨基丙烷-1,3-二羧酸
English alias(r)-1-aminopropane-1,3-dicarboxylic acid | (2R)-2-aminopentanedioate | SR-01000597732 | CHEBI:53375 | GLUTAMIC ACID D-FORM [MI] | C00217 | D-Glutaminic acid | PDSP2_001470 | D-2-Aminoglutaric acid | delta-Glutaminate | D-Glutamic acid, >=99% (TLC) | DB025
CAS number6893-26-1molecular formulaC5H9NO4
molecular weight147.13 g/molExact mass-
PSA101.000 Ųlogp-3.7

numbering system

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physicochemical properties

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Safety information

WGK Germany:
1
Personal protective equipment:
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

Production methods and uses

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MSDS

Found 1 shareMSDS
6893-26-1 | D-Glutamic acid