CAS number：7252-83-7 molecular formula：C4H9BrO2
在10-樟脑磺酸（CSA）存在下，通过与2,3-二醇反应，2-溴-1,1-二甲氧基乙烷（溴乙醛二甲基乙缩醛）可用于合成2,3-O-10-乙缩醛。 2-Bromo-1,1-dimethoxyethane (Bromoacetaldehyde dimethyl acetal) was used in the synthesis of 2,3-O-acetal via reaction with 2,3-diol in the presence of 10-camphorsulphonic acid (CSA). 2-bromo-1,1-dimethoxyethane was used to react with 4-hydroxylbenzaldehyde, and finally aldehyde substituted prodrug was generated by TFA-mediated deacetalization.
| Chinese alias | 溴代乙醛缩二甲醇 | 2,2-二甲氧基溴乙烷 (含稳定剂碳酸钾) | 2-溴-1,1-二甲氧基乙烷 (含稳定剂碳酸钾) | ||
| English alias | 2-Bromo-1,1-dimethoxyethane, 97% | EINECS 230-669-6 | bromoacetaldehyde-dimethylacetal | AC-2029 | FT-0625125 | Q-101943 | 2-bromoacetaldehyde-dimethylacetal | InChI=1/C4H9BrO2/c1-6-4(3-5)7-2/h4H,3H2,1-2H3 | SCHEMBL136821 | 2-bromo-1, 1bis(methyloxy)ethan | ||
| CAS number | 7252-83-7 | molecular formula | C4H9BrO2 |
| molecular weight | 169.02 g/mol | Exact mass | 含0.2 % 碳酸钾稳定剂, 97% |
| PSA | 18.500 Ų | logp | 0.900 |
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