N -马来酰基-β-丙氨酸（3-马来酰亚胺丙酸）是一种脂肪族 N -取代马来酰亚胺。它是用于啮齿类动物药代动力学研究的 EC145（一种叶酸靶向长春花生物碱结合物）稳定溶液的组分之一。 N -马来酰基-β-丙氨酸（3-马来酰亚胺丙酸， N -（2-羧乙基）马来酰亚胺）是以下研究中使用的适用试剂： 降低 Avd (S16C)（具有单点突变 S16C 的亲和素）的生物素结合亲和力。 作为侧链式反应剂，修饰胰蛋白酶肽，导致质量偏移，表明存在半胱氨酸残基。 预先阻断 非洲爪蟾 卵母细胞暴露的半胱氨酸，用作研究 cASIC1a 受体构象变化的表达系统。 它可用于以下研究： 作为角蛋白纤维高温过程中的保护剂。 在四壁分子伞形-八聚精氨酸共轭物合成过程中作为不可断裂的马来酰亚胺基团。 N -马来酰基-β-有机锡羧酸酯的合成-丙氨酸。 功能化金表面与半胱氨酸修饰的肽相互作用。 交联葡聚糖-聚乙二醇水凝胶基质的制备。 N-Maleoyl-β-alanine (3- maleimide propionic acid) is an aliphatic N-substituted maleimide. It is one of the components of EC145 (a folate-targeted vinca alkaloid conjugate) stable solution used for pharmacokinetic study of rodents. N-Maleoyl-β-alanine (3- maleimide propionic acid, N -(2- carboxyethyl) maleimide) is a suitable reagent used in the following research: The biotin binding affinity of Avd (S16C) (avidin with single point mutation S16C) was decreased. As a side chain reaction agent, the trypsin peptide was modified, resulting in mass shift, indicating the presence of cysteine residues. Cysteine exposed by Xenopus oocytes was blocked in advance and used as an expression system to study the conformational changes of cASIC1a receptor. It can be used for the following research: As a protective agent for keratin fibers in high temperature process. As an unbreakable maleimide group in the synthesis process of four-walled molecular umbrella-octa-arginine conjugate. Synthesis of N-Maleoyl-β-Organotin Carboxylate-Alanine. Interaction between functionalized gold surface and cysteine modified peptide. Preparation of crosslinked dextran-polyethylene glycol hydrogel matrix.
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3-Maleimidopropionic Acid
Dangerous GoodsCAS number：7423-55-4 molecular formula：C7H7NO4
overview
compound introduction
Specs
| Chinese alias | N-(2-羧乙基)马来酰亚胺 | 3-马来酰亚胺丙酸 | ||
| English alias | AM20100720 | FT-0604091 | MFCD00043030 | N-(2-Carboxyethyl)maleimide | PD134103 | DTXSID00341526 | STK934575 | 3-(2,5-dioxopyrrol-1-yl)propanoic acid | 3-Maleimidopropionic acid | 3-maleimido-propionic acid | .BETA.-MALEIMIDOPROPIONIC ACID | EN300-227402 | ||
| CAS number | 7423-55-4 | molecular formula | C7H7NO4 |
| molecular weight | 169.13 g/mol | Exact mass | ≥97% |
| PSA | 74.700 Ų | logp | 0.000 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US), Eyeshields, Gloves
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
7423-55-4 | N-Maleoyl-β-alanine.pdf
