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2′,3′-Dideoxycytidine

Dangerous Goods

CAS number：7481-89-2    molecular formula：C9H13N3O3

overview
Specs
numbering system
physicochemical properties
Safety information
Production methods and uses
Related
MSDS
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overview

compound introduction

Application 2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.

Specs

Chinese alias2',3'-二脱氧胞啶 | 扎西他滨 | 双去氧胞嘧啶核酸 | 2',3'-二脱氧胞嘧啶核苷
English alias4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one | Hivid (TN) | bmse000712 | CCG-101050 | HMS2051H18 | NCGC00090705-08 | SCHEMBL3598 | SMR000058253 | Tox21_201655 | BDBM50145605 | Zalcitabine (JAN/USP/INN) | HMS3715O15 | MLS0010553
CAS number7481-89-2molecular formulaC9H13N3O3
molecular weight211.22 g/molExact mass-
PSA88.200 Ųlogp-1.3

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：
GHS08
Signal word：
Warning
Hazard Statement：
H351: 怀疑引起遗传缺陷 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P203: 使用前，获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心，请就医。
WGK Germany：
3
Personal protective equipment：
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECS：
HA3870000

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
7481-89-2 | Zalcitabine.pdf