CAS number：1104-22-9 molecular formula：C25H27Cl2N2·2HCl
Meclizine 2HCl 是histamine H1 receptor拮抗剂,用于治疗恶心，晕动病，也是mCAR（组成型雄烷受体激动剂配体）激动剂配体，也是hCAR的反向激动剂。 Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an inverse agonist for hCAR. A histamine H1 receptor antagonist and pregnane X receptor (PXR) agonist
| Chinese alias | 盐酸美克洛嗪 | ||
| English alias | Meclizine dihydrochloride | 1104-22-9 | Meclizine hydrochloride | Meclozine dihydrochloride | Bonamine | 1-((4-Chlorophenyl)(phenyl)methyl)-4-(3-methylbenzyl)piperazine dihydrochloride | Ancolan dihydrochloride | Meclizine 2HCl | Diadril | Vertizine | Tai | ||
| CAS number | 1104-22-9 | molecular formula | C25H27Cl2N2·2HCl |
| molecular weight | 463.87 g/mol | Exact mass | 2mM in DMSO |
| PSA | 6.500 Ų | logp | - |
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