肝素的具体生物学功能是通过其糖链内部特定结构的功能区与靶蛋白的相互作用来实现的，如肝素分子可以通过糖链内部的特殊的五糖结构GlcNAc/NS(6S)-GlcA-GlcNS(3S,6S)-IdoA(2S)-GlcNS(6S)与抗凝血酶ATIII的相互作用介导对因子Xa的抑制。为了满足客户对各种糖胺聚糖构效关系研究的需要，我们利用肝素酶I/II对肝素进行部分降解，通过凝胶过滤及离子交换HPLC，制备了具有不同聚合度的肝素寡糖及低分子。同时，我们还可以根据客户需求，利用各种特有的结构选择性降解酶和修饰酶，为客户定制具有特殊结构要求的肝素寡糖及低分子。 The specific biological function of heparin is achieved through the interaction between specific functional regions within its sugar chain and target proteins. For example, heparin molecules can inhibit factor Xa through the interaction between the special five sugar structure GlcNAc/NS (6S) - GlcA GlcNS (3S, 6S) - IdoA (2S) - GlcNS (6S) within the sugar chain and antithrombin ATIII. In order to meet the needs of customers for studying the structure-activity relationship of various glycosaminoglycans, we used heparanase I/II to partially degrade heparin, and prepared heparin oligosaccharides and low molecules with different polymerization degrees through gel filtration and ion exchange HPLC. At the same time, we can also customize heparin oligosaccharides and low molecular weight compounds with special structural requirements for customers by utilizing various unique structural selective degradation enzymes and modification enzymes according to their needs.
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
Heparin sodium
Dangerous GoodsCAS number：9041-08-1 molecular formula：
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 9041-08-1 | molecular formula | |
| molecular weight | 6,000-9,000 g/mol | Exact mass | ≥95%(HPLC) |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
WGK Germany：
2
Personal protective equipment：
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS：
MI0850000
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
9041-08-1 | Heparin Sodium for Assays.pdf
