Palmatine chloride

Dangerous Goods

CAS number：10605-02-4 molecular formula：C21H22ClNO4

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Palmatine chloride 是一种不可逆的 IDO-1 抑制剂，对 HEK 293-hIDO-1 和 rhIDO-1 的 IC50 分别为 3 μM 和 157 μM。Palmatine chloride 也能非竞争性抑制西尼罗病毒 (WNV) NS2B-NS3 蛋白酶，IC50 为 96 μM。Palmatine chloride 具有抗癌、抗炎、神经保护、抗细菌、抗病毒活性。 Palmatine chloride is irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine chloride can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine chloride shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities.

Specs

Chinese alias	2,3,9,10-四甲氧基-5,6-二氢异喹啉[2,1-b]异喹啉-7-氯化铵 \| 氯化巴马汀 \| 2,3,9,10-四甲氧基-5,6-二氢异喹啉并[3,2-a]异喹啉-7-鎓氯化物 \| 7,8,13,13a-四氢-2,3,9,10-四甲氧基氯化小檗碱 \| 5,6-二氢-2,3,9,10-四甲氧基二苯并[a,g]氯化喹啉 \| 氯化黄藤素 \| 氯化巴马亭 \| 棕榈碱 \| 7,8,13,13a-四脱氢-2,3,9,10-四甲氧基氯化小檗碱
English alias	MLS002153886 \| P2138 \| UNII-ZJ6W8881Z8 \| Palmatine Hydrochloride,(S) \| ZJ6W8881Z8 \| 2,3-DNT \| 2-Bromo-2-methylpropanoic acid, ethyl ester \| HMS3651D03 \| Fibrauretin \| PALMATINE CHLORIDE [WHO-DD] \| SPECTRUM1500872 \| Dibenzo(a,g)quinolizinium, 5,6-dihydro-2
CAS number	10605-02-4	molecular formula	C21H22ClNO4
molecular weight	387.86 g/mol	Exact mass	-
PSA	40.800 Å²	logp	-

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H302: 吞食有害

Statement of Preventive Measures：

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P330: 漱口 P264+P265: 处理后彻底