All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry

Diethyl chloromalonate

Dangerous Goods

CAS number:14064-10-9    molecular formula:C7H11ClO4

overview

compound introduction

Product Describtion: Diethyl chloromalonate (Diethyl α-chloromalonate) is a 2-halo-1,3-dicarbonyl compound. It participates in K2CO3-catalyzed domino reactions (Michael alkylation, Mannich alkylation, and aldol alkylation) of salicylic aldehyde derivatives to afford functionalized 2,3-dihydrobenzofurans. It reacts with Cs2CO3 in the presence of elemental S8 or Sen to afford the corresponding diethyl thioxo- or selenoxomalonates, which can be trapped in situ with various 1,3-dienes.

Specs

Chinese alias-
English aliasDiethyl chloromalonate, 95% | FT-0637003 | NSC 227952 | MFCD00009140 | Diethyl 2-chloromalonate | Diethyl 2-chloromalonate # | 4-nitro-1H-1,2,3-triazole | EN300-91664 | Ethylmonochloromalonate | Propanedioic acid, chloro-, diethyl ester | BBL103910 | 1,3-
CAS number14064-10-9molecular formulaC7H11ClO4
molecular weight194.61 g/molExact mass≥95%
PSA52.600 Ųlogp1.6

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS09 , GHS05 , GHS07
Signal word:
Danger
Hazard Statement:
H335: 可能引起呼吸道刺激 H314: 造成严重的皮肤灼伤和眼睛损伤 H318: 造成严重的眼睛损伤 H400: 对水生生物有剧毒
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P271: 仅在室外或通风良好的地方使用。 P301+P330+P331: 如误吞咽:漱口。不要诱导呕吐。 P304+P340: 如误吸入:将人转移到空气新鲜处,保
WGK Germany:
3
Personal protective equipment:
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
14064-10-9 | Diethyl chloromalonate.pdf