2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication . 2'-C-Methyladenosine inhibits HCV replicon and NS5B-catalyzed RNA synthesis with IC 50 values of 0.3μM and 1.9 μM, respectively. 2'-C-Methyladenosine also potently inhibits LRV1 in Leishmania guyanensis (Lgy) and Leishmania braziliensis In Vivo 2'-C-Methyladenosine has inhibitory potency for HCV replicon in HB110A cells with an IC 50 values of 0.3μM . 2'-C-Methyladenosine inhibits NS5B-catalyzed RNA synthesis with an IC 50 values of 1.9 μM . 2′-C-methyladenosine potently inhibits LRV1 in Leishmania guyanensis (Lgy) and Leishmania braziliensisMCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 0.3μM (HCV replicon),1.9 μM (NS5B)
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2'-C-Methyladenosine
CAS number：15397-12-3 molecular formula：C11H15N5O4
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Specs
| Chinese alias | 2'-C-甲基腺苷 | ||
| English alias | (2R,3R,4R,5R)-5-Hydroxymethyl-3-methyl-2-(6-methylamino-purin-9-yl)-tetrahydro-furan-3,4-diol | beta-2''-Methyladenosine | Beta-2'-Methyladenosine | (3R)-2-(6-Aminopurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol | BDBM50144948 | (2R,3R,4R,5R)-2-(6- | ||
| CAS number | 15397-12-3 | molecular formula | C11H15N5O4 |
| molecular weight | 281.27 g/mol | Exact mass | ≥99% |
| PSA | 140.000 Ų | logp | -1.300 |
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