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Dexamethasone 21-acetate

Dangerous Goods

CAS number:1177-87-3    molecular formula:C24H31FO6

overview

compound introduction

Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It is also used for replacement therapy in adrenal insufficiency and in a screening test for the diagnosis of cushing's syndrome. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.

Specs

Chinese alias地塞米松 21-乙酸酯
English alias9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate | Dexamethasone acetate
CAS number1177-87-3molecular formulaC24H31FO6
molecular weight434.5 g/molExact mass≥96%
PSA101.000 Ųlogp2.8

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram:
GHS08 , GHS07
Signal word:
Danger
Hazard Statement:
H373: 通过长时间或反复暴露对器官造成损害 H317: 可能引起皮肤过敏反应 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P272: 被污染的工作服不允许离开工作场所 P333+P313: 如发生皮肤刺激或皮疹:求医/就诊。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P203: 使
WGK Germany:
3
Personal protective equipment:
dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECS:
TU4050000

Production methods and uses

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upstream information

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MSDS

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