Hemin

Dangerous Goods

CAS number：16009-13-5 molecular formula：C34H32ClN4O4Fe

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

营养增补剂（铁质强化剂），现代医学公认的防治缺铁性贫血、吸收率高、效果好的往下生物铁源，无铁腥味，不刺激肠胃。是生产天然补铁食品、药品、保健品、化妆品的首选原料。高铁血红素应用于以下应用中：研究菌株和生长条件 · 用于短期菌落测定(培养基由血红素和其他成分组成) · 细胞转染它可用于分析MMV(抗疟药物)疟疾盒化合物对β-血红蛋白形成的抑制作用。 Hemin chloride, a heme oxygenase 1 inducer, is a porphyrin complex that is derived from erythrocytes. At a concentration of 20 mM Hemin chloride demonstrated the significance of heme in myotube maturation by increasing size, number, cross-striations, and contraction frequency and strength of myotubes. The compound has been observed to induce cGMP formation through induction of guanylate cyclase. Hemin chloride has been noted to stimulate calcium-dependent K+ channels and modulate fluid transport and Na+ in the loop of henle in rat studies. Hemin has also been documented to give rise to active chloride secretion in Caco-2 cells. In cadmium injured rat testes, hemin chloride demonstrated anti-apoptotic, antiinflamatory and antioxidant properties. Through reactive oxygen species of ERK-1/2-Elk-1 and NF-κB, hemin chloride has been shown to upregulate Egr-1 expression in vascular smooth muscle cells. It has also been used in solution to prepare agar medium for the cultivation of distinct bacteria. A porphyrin complex heme oxygenase-1 inducer with acts in cellular protection and control

Specs

Chinese alias	血晶素 \| 血晶质 \| 氯化高铁血红素 \| 氯原卟啉IX铁(III), 高铁血红素(氯) \| 氯(原卟啉酸)铁(III) \| 高铁原卟啉IX氯
English alias	Panhematin \| 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(3+);chloride \| Q425165 \| HEMIN [JAN] \| AKOS025146500 \| Hemin chloride is known as an oxidized form of heme. \| HEMIN [WHO-DD] \| hemin c
CAS number	16009-13-5	molecular formula	C34H32ClN4O4Fe
molecular weight	651.96 g/mol	Exact mass	-
PSA	102.000 Å²	logp	-

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS08 , GHS07

Signal word：

Danger

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H317: 可能引起皮肤过敏反应 H334: 吸入可能引起过敏或哮喘病症状或呼吸困难

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P284: 如果通风不良，请佩戴呼吸防护装置。 P271: 仅在室外或通风良好的地方