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Cucurbitacin E

Dangerous Goods

CAS number:18444-66-1    molecular formula:C32H44O8

overview

compound introduction

Cucurbitacin E 是来自 Cucumic melo L 茎的一种天然化合物。Cucurbitacin E 显著抑制 cyclin B1/CDC2 复合物的活性。 Cucurbitacin E is a natural compound which from the climbing stem of Cucumic melo L. Cucurbitacin E significantly suppresses the activity of the cyclin B1/CDC2 complex. Cucurbitacin E has been used as a cofilin inhibitor, It is also used as a F-actin stabilizer to prevent membrane-associated periodic skeleton (MPS) loss and protect from axonal fragmentation.

Specs

Chinese alias-
English aliasMFCD00135936 | NSC106399 | NSC-106399 | C08797 | CUCURBITACIN E [MI] | Cucurbitacine E | DTXSID601030496 | [(E,6R)-6-[(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-y
CAS number18444-66-1molecular formulaC32H44O8
molecular weight556.69 g/molExact mass≥99%
PSA138.000 Ųlogp3.2

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

Found 1 shareMSDS
18444-66-1 | Cucurbitacin E.pdf