Chlorhexidine digluconate solution是双（双胍）家族阳离子广谱抗生素。研究表明，Chlorhexidine digluconate solution通过细菌外膜的失稳而起作用，这导致革兰氏阴性细菌中的周质酶释放。另外，Chlorhexidine digluconate solution抑制氧气的利用，这导致细菌ATP的减少。这些研究还表明，革兰氏阴性细菌的内膜不受溶液的影响，但是对进入细胞的小分子的主动转运有抑制作用。进而，Chlorhexidine digluconate Chlorhexidine digluconate solution is a bis(biguanide) family cationic broad spectrum antibiotic. Studies indicate that Chlorhexidine digluconate solution functions, via destabilization of the outer bacterial membrane, which resulted in the release of periplasmic enzymes in gram negative bacteria. In addition, Chlorhexidine digluconate solution inhibits oxygen utilization which leads to a reduction in bacterial ATP. These studies also indicate that the inner membrane in gram negative bacteria was not affected by the solution, however there was inhibition of active transport for small molecules entering the cell. Furthermore, Chlorhexidine digluconate solution is very effective against bacteria such as|Propionibacterium, Selenomonas|, and cocci resembling|Veillonella|.
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Chlorhexidine digluconate solution
Dangerous GoodsCAS number：18472-51-0 molecular formula：C22H30Cl2N10・2C6H12O7
overview
compound introduction
Specs
| Chinese alias | 1,1'-六亚甲基双[5-(4-氯苯基)双胍]二葡糖酸盐 (约20%于水中) | 葡萄糖酸氯己定, 20% w/v 水溶液 | 1,6-双(N5-[对氯苯基]-N1-双胍)己烷 | 1,1'-六亚甲基双(5-[对氯苯基]双胍) | ||
| English alias | Chlorhexidin glukonatu | Microderm | Plac out | Bactoshield CHG 2% | Chloradine Lube | CHLORHEXIDINE GLUCONATE (USP IMPURITY) | Stomodine F | UNII-0756UWA0SA | Vetasan | Hexi Dip | Hibiclens | UNII-MOR84MUD8E | Betasept | Bioscrub | chlorhexidine biglucon | ||
| CAS number | 18472-51-0 | molecular formula | C22H30Cl2N10・2C6H12O7 |
| molecular weight | 897.76 g/mol | Exact mass | - |
| PSA | 454.000 Ų | logp | - |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS09 , GHS05 , GHS07
Signal word：
Danger
Hazard Statement：
H302: 吞食有害 H318: 造成严重的眼睛损伤 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响
Statement of Preventive Measures：
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P391: 收集溢出物 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急
Production methods and uses
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upstream information
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downstream information
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MSDS
Found 1 shareMSDS
18472-51-0 | Chlorhexidine digluconate solution.pdf
