compound introduction
Prazosin hydrochloride (盐酸哌唑嗪)是α肾上腺素阻断剂，可作用于高血压、焦虑和恐慌症等 哌唑嗪是一种α-肾上腺素能阻滞剂。它被视为一种周围血管舒张抗高血压药物。哌唑嗪是喹唑啉的衍生物。 应用： 盐酸哌唑嗪已用于： • 阻断介导小鼠交感血管收缩的 α1 肾上腺素能受体 • 作为 α1-肾上腺素受体阻滞剂，大鼠灌胃给药 • 作为血管扩张剂，与胰岛素一起注入小鼠左心室，评价其对肾功能的影响 Prazosin is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder. razosin hydrochloride has been used: • to block the α1adrenergic receptors that mediate sympathetic vasoconstriction in mice. • as an α1-adrenoceptor blocker,administered intragastrically in rats. • as a vasodilator,administered together with inuslin into the left ventricle of mice for the assessment of its effects on renal functions.
