compound introduction
三磷酸尿苷二钠为白色粉末，易溶于水，不溶于乙醇。在pH2条件下A250/A260 =0.75±0.05; A280/A260 =0.38±0.05; λmax=262±1nm。 应用： UTP 已被用作 P2 受体激活剂，研究其对 MC3T3-E1 和 UMR-106 细胞质子外流的影响。还研究了 UTP 与盐酸阿米洛利雾化溶液联合治疗囊性纤维化。 尿苷 5′-三磷酸盐曾用于一项研究显示氟西汀 (FLX) 通过增加腺苷 5′ 的胶质传递而介导其抗抑郁作用-三磷酸盐 (ATP)。 Application： UTP has been used as a P2 receptor activator to study its effects on proton efflux in MC3T3-E1 and UMR-106 cells. UTP has also been studied in combination with amiloride hydrochloride in nebulizer solutions for treating cystic fibrosis. Uridine 5′-triphosphate has been used in a study to show that fluoxetine (FLX), mediates its anti-depressive effect by increasing the gliotransmission of adenosine 5′-triphosphate (ATP).
