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Crospovidone

Dangerous Goods

CAS number:25249-54-1    molecular formula:(C6H9NO)n

overview

compound introduction

产品描述: 交联聚乙烯基吡咯烷酮(PVP-P)作为配方中的超级崩解剂,其性能和多功能性无与伦比。 它结合了不同的机制,在低浓度(1-5%)下实现快速片剂崩解。由于其粘弹性,C494178具有高度的可压缩性,从而使片剂具有更高的拉伸强度和更低的脆性。C494178的扫描电子显微镜图像显示出具有大表面积的粒状和多孔结构。它增强了难溶性药物活性物质的溶解,由于其非离子性质,它不承担与阳离子原料药相互作用的任何风险。 C494178有两种粒度可供选择,以满足不同的应用要求。 优点: 1.低浓度快速崩解(1-5%) 2.通过组合崩解机制(芯吸、形状恢复和膨胀)发挥作用,从而赋予其作为配方中超级崩解剂的无与伦比的多功能性 3.适用于直接压缩、湿法制粒和干法制粒 4.由于高压缩性,片剂拉伸强度增加,易碎性降低 5.即使在更高浓度(10%)下也不会形成凝胶——ODT的理想选择 产品规格与参数 项目号

Specs

Chinese alias-
English aliasPolyvinylpyrrolidone
CAS number25249-54-1molecular formula(C6H9NO)n
molecular weight111.140 g/molExact massUSP
PSA20.300 Ųlogp0.400

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Safety information

WGK Germany:
1

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