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Doxorubicin hydrochloride

Dangerous Goods

CAS number:25316-40-9    molecular formula:C27H29NO11·HCl

overview

compound introduction

Doxorubicin (Adriamycin)是一种抗生素类试剂,抑制DNA拓扑异构酶II,且诱导DNA损伤和凋亡。抗肿瘤抗生素,在心脏线粒体DNA方面有阿霉素的效果。反相转录酶和RNA聚合酶的抑制剂,免疫抑制剂;可插入DNA链中。临床上是癌症化疗剂、主要用于急、慢性白血病、恶性淋巴瘤。 Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. A Topo II inhibitor, DNA intercalator and powerful cytotoxic agent

Specs

Chinese alias盐酸多柔比星 | 羟基柔红霉素盐酸盐 | 阿霉素盐酸盐 | 多柔比星盐酸盐 | 阿霉素
English aliasDoxorubicini hydrochloridum | Lipodox | Lipo-Dox | Doxorubicin (hydrochloride) | (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | Doxorubi
CAS number25316-40-9molecular formulaC27H29NO11·HCl
molecular weight579.98 g/molExact mass-
PSA206.000 Ųlogp-

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS08 , GHS07
Signal word:
Danger
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H302: 吞食有害 H360: 可能损害生育力或未出生的孩子 H340: 可能导致遗传缺陷 H350: 可能导致癌症
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P281: 根据需要使用个人防护设备。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P362+P364: 脱掉沾污的衣服,清洗后方可
WGK Germany:
3
Personal protective equipment:
Eyeshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges
RTECS:
QI9295900

Production methods and uses

No production method and use information yet

Related

upstream information

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downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
25316-40-9 | Doxorubicin hydrochloride | Doxorubicin hydrochloride