compound introduction
非普拉宗是一种非甾体类抗炎化合物。值得注意的是，非普拉宗在结构上与苯基丁酮相似，并已用于分析细胞色素P-450诱导的研究中。还据报道，非普拉宗诱导了P450 2B家族的细胞色素。据报道，通过非普拉宗与哺乳动物CYP2B相互作用的分子模型，CYP2B代谢非普拉宗会在化合物侧链的两个位置发生。 Feprazone is a non-steroidal, anti-inflammatory compound. Feprazone is noted to be structurally similar to phenylbutazone and has been utilized in research studies analyzing the induction of cytochrome P-450. Feprazon was also reported to induce the P450 2B family of cytochromes. Metabolization of Feprazone by CYP2B is reported to occur at two positons on the side chains of the compound through a molecular modeling of the interaction of the Feprazon and mammalian CYP2B.
