Diltiazem HCl 是一种Benzothiazepine衍生物，具有舒张血管的作用，由于其抑制钙离子在膜的功能。Diltiazem hydrochloride is used to treat cardiovascular diseases, such as angina and hypertension. It acts as an inhibitor to cytochrome P450 3A (CYP3A). Diltiazem might be associated with maculopapular rashes, urticaria and pruritus.(+)-cis-Diltiazem hydrochloride has been used: · to study its effects on diffusion and release in monolithic dispersion matrix · to study its neuroprotective effects in retinitis pigmentosa (RP) models · as an antagonist against the Cav1.2 L-type calcium channels (LTCCs) Diltiazem HCl (Tiazac) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.Diltiazem hydrochloride is used to treat cardiovascular diseases, such as angina and hypertension. It acts as an inhibitor to cytochrome P450 3A (CYP3A). Diltiazem might be associated with maculopapular rashes, urticaria and pruritus.
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Diltiazem HCl
Dangerous GoodsCAS number：33286-22-5 molecular formula：C22H26N2O4S·HCl
overview
compound introduction
Specs
| Chinese alias | 盐酸地尔硫卓 | (+)-顺-地尔硫卓盐酸盐 | 硫氮卓酮 | 顺-(+)-5-[(2-二甲氨基)乙基]-2-(4-甲氧基苯基)-3-乙酰氧基-2,3-二氢-1,5-苯并硫氮杂卓-4(5H)酮盐酸盐 | (2S,3S)-(+)-顺式-3-乙酰氧基-5-(2-二甲基氨基乙基)-2,3-二氢-2-(4-甲氧基苯基)-1,5-苯并硫氮杂-4(5H)- 酮 盐酸盐 | ||
| English alias | CRD-401 | (+)-cis-Diltiazem hydrochloride | Britiazim | Farmabes | Myonil | Cardizem Retard | Gadoserin | Presoken | Dinisor Retard | Cardizem LA | Diltan | Miocardie | Bruzem | Diltiasyn | Diltiazem GNR | Tiadil | Mono-Tildiem | Syn-Diltiazem | Apo-dilti | ||
| CAS number | 33286-22-5 | molecular formula | C22H26N2O4S·HCl |
| molecular weight | 450.98 g/mol | Exact mass | ≥98% |
| PSA | 84.400 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US)， Eyeshields， Gloves
RTECS：
DL0310000
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
33286-22-5 | (2S-cis)-3-Acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride.pdf
