compound introduction
3-丁炔-2-酮在手性氨基膦的催化下可与邻甲苯磺酰基苯丙二酸酯发生不对称的双迈克尔反应生成二氢吲哚。它可与含氮的束缚二酸进行双迈克尔反应生成胡椒酸衍生物。 产品用途： 3-丁炔-2-酮可用于克罗烷二萜（+/-）-沙卡菌素的合成。它可作为氯化镓（III）介导的立体选择性共轭芳基化的底物用于生成(E)-α,β-不饱和 酮。 Product Description Under the catalysis of chiral aminophosphine, 3-butyn-2-one can react with o-toluenesulfonylbenzenemalonate in an asymmetric bis-Michael reaction to form indoline. It can react with nitrogen-containing bound diacids to produce piperonic acid derivatives. Product Application 3-Butyn-2-one can be used in the synthesis of Cropane diterpene (+/-)-Sakamectin. It can be used as a substrate for stereoselective conjugated arylation mediated by gallium (III) chloride to generate (E)-α,β-unsaturation.
