Product Description Carboplatin is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of carboplatin was inspired from the efficacy of its progenitor, Cisplatin (sc-200896), the first of this class of antineoplastic agents. The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules, including enzymes, which might play a role in their mechanism of action. An antitumor agent that binds to DNA leading to apoptosis Product Application Carboplatin has been used: in chemotherapy-induced thrombocytopenia mouse model and treatment to induce cell death in a large subset of colorectal cancer cells in the evaluation of cell proliferation and chemosensitivity as a positive control for suppressed cell growth Product class hAPIs, Metal based hAPIs Chemical properties Chemical formula C 6 H 12 N 2 O 4 Pt Empirical formula [Pt(NH 3 ) 2 (cbdc)] Molecular weight 371.25 Metal Pt Theoretical metal content 53 Physical state powder Color white
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Carboplatin
Dangerous GoodsCAS number：41575-94-4 molecular formula：C6H12N2O4Pt
overview
compound introduction
Specs
| Chinese alias | Carboplatin | 卡波铂 | 碳铂 | 顺-二氨-1,1-环丁烷基二羟酸铂 | 顺-二氨-1,1-环丁烷基二羧酸铂 | 顺式-1,1-环丁烷二羧酸二氨铂 | 顺 - 二氨基(1,1-环丁烷二羧酸)铂 | 顺-二胺(1,1-环丁烷二羧酸)铂(II) | ||
| English alias | 41575-94-4 | Carboplatin | Paraplatin | Cbdca | Carboplatinum | MFCD00070464 | NSC-241240 | cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II) | cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) | 1,1-Cyclobutanedicarboxylate diammine platinum(II | ||
| CAS number | 41575-94-4 | molecular formula | C6H12N2O4Pt |
| molecular weight | 371.25 g/mol | Exact mass | - |
| PSA | 76.600 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08 , GHS07
Signal word：
Danger
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H302: 吞食有害 H317: 可能引起皮肤过敏反应 H334: 吸入可能引起过敏或哮喘病症状或呼吸困难 H312: 皮肤接触有害 H332: 吸入有害 H372: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子 H340: 可能导致遗传缺陷 H302+H312+H332: 吞咽，皮肤接触或吸入有害。 H362: 可能对母乳喂养的孩子造成伤害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P284: 如果通风不良，请
WGK Germany：
3
Personal protective equipment：
Eyeshields， Faceshields， full-face particle respirator type N100 (US)， Gloves， respirator cartridge type N100 (US)， type P1 (EN143) respirator filter， type P3 (EN 143) respirator cartridges
RTECS：
TP2300000
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
41575-94-4 | Carboplatin, United States Pharmacopeia(USP) Reference Standard.pdf
