Tobramycin sulfate is used as an antibiotic which is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. It is used to inhibit bacterial protein synthesis at the level of 30S (16S rRNA) and 70S ribosomal complex assembly. It is used to treat pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis and other soft-tissue infections. It is a potential therapy for sinus infections1.
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Tobramycin sulfate
Dangerous GoodsCAS number:49842-07-1 molecular formula:C18H37N5O9·H2O4S
overview
compound introduction
Specs
| Chinese alias | (2S,3R,4S,5S,6R)-4-氨基-2-[(1S,2S,3R,4S,6R)-4,6-二氨基-3-[(2R,3R,5S,6R)-3-氨基-6-(氨基甲基)-5-羟基恶烷-2-基]氧基-2-羟基环己基]氧基-6-(羟基甲基)恶烷-3,5-二醇半(五硫酸盐) | ||
| English alias | Nebcine | MFCD00133864 | SMR000058891 | (2S,3R,4S,5S,6R)-4-Amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol Sulfate | Tobramycin (sulfate) | A | ||
| CAS number | 49842-07-1 | molecular formula | C18H37N5O9·H2O4S |
| molecular weight | 565.59 g/mol | Exact mass | ≥98% |
| PSA | 351.000 Ų | logp | - |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS08 , GHS07
Signal word:
Danger
Hazard Statement:
H312: 皮肤接触有害 H332: 吸入有害 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P203: 使用前,获取、阅读并遵守所有安全说明。 P3
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upstream information
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MSDS
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