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Cefsulodin Sodium Salt Hydrate

Dangerous Goods

CAS number:52152-93-9    molecular formula:C22H19N4NaO8S2·xH2O

overview

compound introduction

Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics. The compound displays a mechanism of action like many β lactam antibiotics through inhibition of cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) crosslinking of peptidoglycan resulting in inhibition of the final transpeptidation step. Through the inability for Cefsulodin sodium salt hydrate to inhibit cefsulodin-resistant mutants of Pseudomonas aeruginosa PAO4089 growth displayed that Cefsulodin sodium salt hydrate may compete with PBP3 in addtion to PBP1A and PBP1B. Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics. The compound displays a mechanism of action like many β lactam antibiotics through inhibition of cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) crosslinking of peptidoglycan resulting in inhibition of the final transpeptidation step. Through the inability for Cefsulodin sodium salt hydrate to inhibit cefsulodin-resistant mutants of Pseudomonas aeruginosa PAO4089 growth displayed that Cefsulodin sodium salt hydrate may compete with PBP3 in addtion to PBP1A and PBP1B. A β lactam antibiotic.

Specs

Chinese alias头孢磺吡苄钠盐水合物 | 头孢磺啶钠 | 达克舒林 | 磺吡芐头孢菌素 | 头孢磺吡芐 | 头孢磺吡酮
English aliascefsulodin sodium | 52152-93-9 | CEFSULODIN SODIUM SALT | Sulcephalosporin | Cefsulodin sodium salt hydrate | Takesulin | Cefsulodine sodium | Abbott-46811 | Cefsulodin (sodium) | Pseudomonil | Cefsulodin Sodium Salt, Hydrate | Cefomonil | Pseudocef | Til
CAS number52152-93-9molecular formulaC22H19N4NaO8S2·xH2O
molecular weight554.52(as Anhydrous)Exact mass10mM in DMSO
PSA227.000 Ųlogp-

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS08 , GHS07
Signal word:
Danger
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H317: 可能引起皮肤过敏反应 H334: 吸入可能引起过敏或哮喘病症状或呼吸困难
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P284: 如果通风不良,请佩戴呼吸防护装置。 P271: 仅在室外或通风良好的地方

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

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