Estramustine phosphate sodium

Dangerous Goods

CAS number：52205-73-9 molecular formula：C23H30Cl2NNa2O6P

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Estramustine phosphate sodium (EMP, Emcyt, Estracyt) is an antitumour drug with a unique dual mode of action. Estrone and estradiol, products of the metabolism of estramustine phosphate sodium, have shown antigonadotrophic activity resulting in reduced testosterone levels. Estramustine(the cytotoxic metabolite produced by dephosphorylation of estramustine phosphate sodium) is an antiprostatic tumor drug with antimicrotubule effects.

Specs

Chinese alias	雌莫司丁磷酸钠 \| [3-[双(2-氯乙基)氨基甲酰氧基]-13-甲基-6,7,8,9,11,12,14,15,16,17-十氢环戊[a]菲蒽-17-基]磷酸二钠',
English alias	Estramustine 17-(Dihydrogenphosphate) Disodium Salt \| Leo-299 \| Estramustine phosphate sodium hydrate \| AC-1612 \| disodium (17beta)-3-{[bis(2-chloroethyl)carbamoyl]oxy}estra-1(10),2,4-trien-17-yl phosphate \| Estramustine sodium phosphate \| ESTRAMUSTINE SO
CAS number	52205-73-9	molecular formula	C23H30Cl2NNa2O6P
molecular weight	564.35 g/mol	Exact mass	≥95%
PSA	102.000 Å²	logp	-

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS08

Signal word：

Danger

Hazard Statement：

H351: 怀疑引起遗传缺陷 H373: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子 H361: 怀疑破坏生育力或未出生的孩子

Statement of Preventive Measures：

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P203: 使用前，获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心，请就医。 P319: 如果你感到不适，请寻求医疗帮助。