Nicardipine hydrochloride is the hydrochloride salt preparation of Nicardipine and a potent L-type calcium channel protein inhibitor. Nicardipine is described to alter cytochrome P-450 3A expression through induction of CYP3A. Nicardipine blockade of Ca2+ channels has been correlated to antihypertensive effects. Nicardipine hydrochloride is the hydrochloride salt preparation of Nicardipine and a potent L-type calcium channel protein inhibitor. Nicardipine is described to alter cytochrome P-450 3A expression through induction of CYP3A. Nicardipine blockade of Ca2+ channels has been correlated to antihypertensive effects. A potent calcium channel protein inhibitor
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Nicardipine hydrochloride
Dangerous GoodsCAS number:54527-84-3 molecular formula:C26H29N3O6·HCl
overview
compound introduction
Specs
| Chinese alias | 盐酸诺拉替坦 | ||
| English alias | Nicardipine (Hydrochloride) | NICARDIPINE HYDROCHLORIDE [MI] | HMS1569M07 | Loxen | MLS001146898 | NICARDIPINE HYDROCHLORIDE (EP MONOGRAPH) | Vasonase | 2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate | ||
| CAS number | 54527-84-3 | molecular formula | C26H29N3O6·HCl |
| molecular weight | 515.99 g/mol | Exact mass | 10mM in DMSO |
| PSA | 114.000 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS06
Signal word:
Danger
Hazard Statement:
H301: 吞咽会中毒 H311: 皮肤接触有毒 H331: 吸入会中毒
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P403+P233: 存放在通风良
WGK Germany:
3
Personal protective equipment:
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECS:
US7972100
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
54527-84-3 | Nicardipine Hydrochloride, United StatesPharmacopeia (USP) Reference Standard.pdf





