阿维菌素B1a是一种大环内酯,构成了用于控制牲畜寄生线虫的抗蠕动阿维菌素的大部分。阿维菌素B1a还充当杀虫剂和杀螨剂。阿维菌素在商业上用作动物健康,农业和人类感染中的抗寄生虫剂。研究表明,它可以激活和抑制哺乳动物脑中的GABA | A |Rα1(γ-氨基丁酸A)受体功能。 Avermectin B1a is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. Avermectin B1a also acts as an insecticide and acaricide. The avermectins are used commercially as antiparasitic agents in animal health, agriculture and human infections. Research shows that it can activate and inhibit GABA|A|Rα1 (gamma-aminobutyric acidA) receptor function in mammalian brain.
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Avermectin B1a
Dangerous GoodsCAS number:65195-55-3 molecular formula:C48H72O14
overview
compound introduction
Specs
| Chinese alias | 伊维菌素EP杂质A | ||
| English alias | AKOS027327844 | CHEBI:29534 | Abamectina | AB00918538-03 | Abamectin B1a | Abamectin komponente B1a | WLN: T6O BUTJ FVH | J-519606 | UNII-5E2OT6T2PS | Abamectin B1a 1000 microg/mL in Acetonitrile | Cresyl alpha-toluate, p- | 5-O-Demethylavermectin A1a; Sp | ||
| CAS number | 65195-55-3 | molecular formula | C48H72O14 |
| molecular weight | 873.1 g/mol | Exact mass | ≥95% |
| PSA | 170.000 Ų | logp | 3.800 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS06 , GHS08 , GHS09
Signal word:
Danger
Hazard Statement:
H311: 皮肤接触有毒 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响 H300: 吞咽致命 H330: 吸入致命 H372: 通过长时间或反复暴露对器官造成损害 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P284: 如果通风不良,请佩戴呼吸防护装置。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P304+P340: 如误
Production methods and uses
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MSDS
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