(R,R)-(-)-N,N′-Dimethyl-1,2-cyclohexanediamine is a N,N′-dimethylated derivative of enantiopure 1,2-diaminocyclohexane. It can be formed during the hydrolysis of (R3a,R7a)-1,3-(dimethyl)-2-phenyl-2,3,3a,4,5,6,7,7a-octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide using HCl-methanol. (R,R)-(-)-N,N′-Dimethyl-1,2-cyclohexanediamine is a N,N′-dimethylated derivative of enantiopure 1,2-diaminocyclohexane. It can be formed during the hydrolysis of (R3a,R7a)-1,3-(dimethyl)-2-phenyl-2,3,3a,4,5,6,7,7a-octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide using HCl-methanol. application： (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine can be used: As a ligand in the preparation of 4H-benzo[f]imidazo[1,4]diazepin-6-one through multi-component Ullmann coupling reaction. In one of the key synthetic steps for the preparation of tricyclic γ-secretase modulators. To prepare chiral fluorous diamino-diol proligand, which is used in the synthesis of zirconium metal complexes applicable as catalysts in 1-hexene polymerization.
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(R,R)-(-)-N,N′-Dimethyl-1,2-cyclohexanediamine
Dangerous GoodsCAS number：68737-65-5 molecular formula：C8H18N2
overview
compound introduction
Specs
| Chinese alias | (1R,2R)-(-)-1,2-双(甲氨基)环己烷 | ||
| English alias | GEO-02658 | N,N'-Dimethyl-(1R,2R)-1,2- cyclohexanediamine | racemic trans-N,N'-dimethyl-cyclohexane-1,2-diamine | racemic trans-N,N'-dimethylcyclohexane-1,2-diamine | (+/-)-trans-N,N'-bismethyl-1,2-cyclohexane diamine | (1r,2r)-diaminomethylcyclohexane | | ||
| CAS number | 68737-65-5 | molecular formula | C8H18N2 |
| molecular weight | 142.24 g/mol | Exact mass | ≥97%(GC) |
| PSA | 24.100 Ų | logp | 0.700 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS05 , GHS07
Signal word：
Danger
Hazard Statement：
H314: 造成严重的皮肤灼伤和眼睛损伤 H302: 吞食有害 H318: 造成严重的眼睛损伤
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P301+P330+P331: 如误吞咽：漱口。不要诱导呕吐。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P363: 再次使用之前，请清洗受污染的衣物。 P330: 漱
WGK Germany：
3
Personal protective equipment：
Faceshields， full-face respirator (US)， Gloves， Goggles， multi-purpose combination respirator cartridge (US)， type ABEK (EN14387) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
68737-65-5 | (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediam ine.pdf
