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Bepridil hydrochloride monohydrate

Dangerous Goods

CAS number:74764-40-2    molecular formula:C24H37ClN2O2

overview

compound introduction

Bepridil hydrochloride 是一种钙通道蛋白抑制剂和拮抗剂,可增加红细胞的表面积。盐酸贝普地尔已被证明是一种造血药,可引起脱氧的镰状红细胞内吞并降低细胞的可变形性。此外,据报道盐酸贝普地尔阻断了膜中的Na | + |和Ca | 2+ |交换。盐酸贝普地尔还显示出作为体外增殖的有效抑制剂的能力。盐酸贝普地尔是NCX的抑制剂。 Bepridil hydrochloride is a calcium channel protein inhibitor and antagonist that increases the surface area of red blood cells. Bepridil hydrochloride has been shown to be a stomatocytic agent that causes endocytosis and lowers cell deformability in deoxygenated sickle erythrocytes. Furthermore, Bepridil hydrochloride has been reported to block Na|+|and Ca|2+|exchange through membranes. Bepridil hydrochloride also demonstrates the ability to act as an effective inhibitor of|in vitro cell|proliferation. Bepridil hydrochloride is an inhibitor of NCX.

Specs

Chinese alias-
English aliasBepridil hydrochloride hydrate (JAN) | CERM-1978 | DTXSID5040176 | HY-16952A | BEPRIDIL HYDROCHLORIDE HYDRATE [JAN] | BEPRIDIL HYDROCHLORIDE MONOHYDRATE [MI] | SCHEMBL3986618 | AKOS024408879 | NSC-758390 | BEPRIDIL HYDROCHLORIDE [ORANGE BOOK] | s9566 | Or
CAS number74764-40-2molecular formulaC24H37ClN2O2
molecular weight421.02 g/molExact mass≥98%
PSA16.700 Ųlogp-

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram:
GHS08 , GHS07
Signal word:
Danger
Hazard Statement:
H317: 可能引起皮肤过敏反应 H334: 吸入可能引起过敏或哮喘病症状或呼吸困难 H332: 吸入有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P501: 将内容物/容器处理到。。。 P284: 如果通风不良,请佩戴呼吸防护装置。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P272: 被污染的工作服不允许离开工作场所 P333+P313: 如发生皮肤刺激或皮疹:
WGK Germany:
2
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS:
UY1162000

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

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