CAS number：75747-14-7 molecular formula：C31H43N3O8
17-AAG (Tanespimycin)是一种有效的HSP90抑制剂，IC50为5 nM，作用于从肿瘤细胞提取的HSP90比作用于从正常细胞提取的HSP90结合亲和力高100倍。A potent Hsp90 inhibitor for tumor cells 17-AAG (Tanespimycin) is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. A potent Hsp90 inhibitor for tumor cells
| Chinese alias | 替拉替尼 | 坦螺旋霉素 | 17-烯丙基氨基格尔德霉素 | 17-（烯丙基氨基）-17-去甲氧基格尔德霉素 | ||
| English alias | Allylamino-17-demethoxygeldanamycin, 17- | CNF1010 | CNF-1010 | 17-(Allylamino) Geldanamycin | BRN 0888706 | NSC330507 | NSC-330507 | SCHEMBL309550 | CHEBI:64153 | NCGC00163424-01 | KOS 953 | Tanespimycin (17-AAG) | C76418 | UNII-4GY0AVT3L4 | 17AAG | 17-A | ||
| CAS number | 75747-14-7 | molecular formula | C31H43N3O8 |
| molecular weight | 585.69 g/mol | Exact mass | ≥98% |
| PSA | 166.000 Ų | logp | 2.600 |
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