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Enalaprilat

Dangerous Goods

CAS number:76420-72-9    molecular formula:C18H28N2O7

overview

compound introduction

Enalaprilat is the active form of Enalapril. Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, sμggested to be more potent than Captopril. Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.An active metabolite of Enalapril. Enalaprilat is the active form of Enalapril. Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril. Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway. An active metabolite of Enalapril.

Specs

Chinese alias依那普利拉
English aliasAB00698268_09 | Enalaprilat,(S) | L-PROLINE, 1-(N-(1-CARBOXY-3-PHENYLPROPYL)-L-ALANYL)-, (S)- | NCGC00164593-02 | DTXSID0048975 | Q508Q118JM | SCHEMBL37289 | 2-(Ethylamino)-4-(isopropylamino)-6-(methylthio)-s-triazine | MFCD00865786 | Tox21_113430 | Enala
CAS number76420-72-9molecular formulaC18H28N2O7
molecular weight384.42 g/molExact mass-
PSA107.000 Ųlogp-0.700

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。

Production methods and uses

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upstream information

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downstream information

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MSDS

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