Enalaprilat is the active form of Enalapril. Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, sμggested to be more potent than Captopril. Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.An active metabolite of Enalapril. Enalaprilat is the active form of Enalapril. Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril. Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway. An active metabolite of Enalapril.
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Enalaprilat
Dangerous GoodsCAS number:76420-72-9 molecular formula:C18H28N2O7
overview
compound introduction
Specs
| Chinese alias | 依那普利拉 | ||
| English alias | AB00698268_09 | Enalaprilat,(S) | L-PROLINE, 1-(N-(1-CARBOXY-3-PHENYLPROPYL)-L-ALANYL)-, (S)- | NCGC00164593-02 | DTXSID0048975 | Q508Q118JM | SCHEMBL37289 | 2-(Ethylamino)-4-(isopropylamino)-6-(methylthio)-s-triazine | MFCD00865786 | Tox21_113430 | Enala | ||
| CAS number | 76420-72-9 | molecular formula | C18H28N2O7 |
| molecular weight | 384.42 g/mol | Exact mass | - |
| PSA | 107.000 Ų | logp | -0.700 |
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
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