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Enoximone

Dangerous Goods

CAS number：77671-31-9    molecular formula：C12H12N2O2S

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physicochemical properties
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overview

compound introduction

Enoximone 是一种正性肌力血管舒张剂，也是一种选择性的磷酸二酯酶 III (PDE3) 抑制剂，IC50 为 5.9 μM。Enoximone 通过抑制 cGMP 抑制的 PDE 来诱导血管舒张并增加细胞内 cAMP 水平。Enoximone 还表现出 PDE4 抑制作用，对心肌 PDE4A 的 IC50 为 21.1 μM。

Specs

Chinese alias依诺昔酮 | 4-甲基-5-[4-(甲硫基)苯甲酰基]-1,3-二氢-2H-咪唑-2-酮 | 1,3-二氢-4-甲基-5-[4-(甲硫基)苯甲酰基] -2H-咪唑-2-酮
English aliasDTXSID8045147 | Enoximone, solid | SCHEMBL44049 | Enoximonum | HMS3369O01 | MDL-17,043 | MLS002172494 | NCGC00015400-03 | 5-methyl-4-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one | DTXCID6025147 | ENOXIMONE [WHO-DD] | GTPL9063 | MDL-17043 | ENOXIMONE [MAR
CAS number77671-31-9molecular formulaC12H12N2O2S
molecular weight248.3 g/molExact mass-
PSA83.500 Ųlogp1.6

numbering system

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physicochemical properties

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Safety information

WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， half-mask respirator (US)， multi-purpose combination respirator cartridge (US)

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