CAS number：80621-81-4 molecular formula：C43H51N3O11
Rifaximin是一种胃肠道选择性的抗生素 (antibiotic)，与细菌 DNA 依赖性 RNA 聚合酶的 β 亚基结合，从而抑制细菌 RNA 的合成 (bacterial RNA synthesis)。与革兰氏阴性菌（MIC：8-50 毫克/毫升）相比，Rifaximin对革兰氏阳性菌株（MIC：0.03-5 毫克/毫升）的敏感性更高。 Rifaximin 是Rifamycin SV衍生的一种半合成的，非全身性抗生素，具有抗菌活性。 Rifaximin, an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. An antibiotic that inhibits RNA synthesis and activates PXR.
| Chinese alias | 利福昔明 | 利福西亚胺 | ||
| English alias | (2S,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-1,1 | HSDB 7834 | (2S,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-25-(Acetyloxy)-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11,16,20,22,24,26-o | ||
| CAS number | 80621-81-4 | molecular formula | C43H51N3O11 |
| molecular weight | 785.88 g/mol | Exact mass | - |
| PSA | 198.000 Ų | logp | 6.9 |
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