普伐他汀是一种竞争性HMGCR(HMG-CoA还原酶)抑制剂,可有效阻断胆固醇合成(K | i |〜1 nM)。普伐他汀具有心脏保护作用,还可以作为免疫调节剂和ras p21异戊二烯化的抑制剂。 Pravastatin is a competitive HMGCR (HMG-CoA reductase) inhibitor that potently blocks cholesterol synthesis (K|i|~1 nM). Pravastatin offers cardioprotection and also acts as an immunomodulator and as an inhibitor of ras p21 isoprenylation.
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Pravastatin
Dangerous GoodsCAS number:81093-37-0 molecular formula:C23H36O7
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | pravastatin | 81093-37-0 | Pravastatinum | Pravastatina | Pravastatine | Eptastatin | Pravachol | Pravator | Pravastatin acid | Pravastatinum [Latin] | CCRIS 7557 | UNII-KXO2KT9N0G | KXO2KT9N0G | Pravastatin (INN) | (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy- | ||
| CAS number | 81093-37-0 | molecular formula | C23H36O7 |
| molecular weight | 424.53 g/mol | Exact mass | 10mM in DMSO |
| PSA | 124.000 Ų | logp | 1.600 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS08 , GHS09
Signal word:
Danger
Hazard Statement:
H411: 对水生生物有毒并具有长期持续影响 H314: 造成严重的皮肤灼伤和眼睛损伤 H228: 易燃固体
Statement of Preventive Measures:
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P370+P378: 火灾时:使用干砂、干粉或抗醇泡沫灭火。 P210: 远离热源,热表面,火花,明火和其他点火源。 - 禁止抽烟。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P240: 地面/粘结容器和接收设备 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P241: 使用防爆的[电气/通风/照明/..
RTECS:
QJ7185000
UN Number:
3077
Packing Group:
III
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
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