Trimetrexate glucuronate (NSC 352122) 是一种叶酸拮抗剂,可以抑制二氢叶酸还原酶 (dihydrofolate reductase),从而阻止嘌呤核苷酸和胸苷酸的合成,影响 DNA 和 RNA 合成。具有潜在的抗肿瘤活性, 也可用于抑制肺孢子菌肺炎。
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Trimetrexate Glucuronate
CAS number:82952-64-5 molecular formula:C25H33N5O10
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 82952-64-5 | molecular formula | C25H33N5O10 |
| molecular weight | 563.6 g/mol | Exact mass | ≥98% |
| PSA | 253.000 Ų | logp | - |
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