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Nafamostat Mesylate

Dangerous Goods

CAS number：82956-11-4    molecular formula：C19H17N5O2·2CH4O3S

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Specs
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physicochemical properties
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overview

compound introduction

Nafamostat Mesylate是一种抗凝血剂。A highly effective tryptase inhibitor. Nafamostat甲磺酸盐是广谱的丝氨酸蛋白酶抑制剂，血管舒缓素抑制剂，能抑制血液凝固，还是潜在的补体抑制剂。Nafamostat甲磺酸盐通过降低颗粒酶活性和 CTL 细胞溶解抑制T细胞自身反应活性。Nafamostat mesylate 可抑制SARS-CoV-2 的激活。 Nafamostat mesilate is a synthetic serine protease inhibitor, used as an anticoagulant during hemodialysis. A highly effective tryptase inhibitor.

Specs

Chinese alias甲磺酸萘莫司他 | 6-甲脒基-2-萘基-4-胍基苯甲酸酯二(甲磺酸盐) | 4-胍基苯甲酸6-甲脒基-2-萘基酯双(甲磺酸盐)
English aliasFUT-175 | 6-amidino-2-naphthyl 4-guanidino-benzoate dimethanesulphonate | CCG-207877 | Nafamstat | 6-AMIDINO-2-NAPHTHYL P-GUANIDINOBENZOATE, DIMETHANESULPHONATE | nafamostat mesilate | NAFAMOSTAT MESILATE [WHO-DD] | 4-Guanidinobenzoic Acid 6-Amidino-2-nap
CAS number82956-11-4molecular formulaC19H17N5O2·2CH4O3S
molecular weight539.58 g/molExact mass≥98%
PSA266.000 Ųlogp-

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS08
Signal word：
Warning
Hazard Statement：
H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P203: 使用前，获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心，请就医。
Personal protective equipment：
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS：
DG2736000

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