compound introduction
Minoxidil sulfate (U-58838) 是K +通道激动剂和强壮的血管平滑肌松弛剂。已显示它可以放松去甲肾上腺素的收缩，据报道是血管扩张药。硫酸米诺地尔在同基因和异基因大鼠研究中已被用来更好地了解血脑肿瘤屏障，并已证明可增加肿瘤的通透性。 应用： 米诺地尔硫酸盐(MXS)已用于研究其作为药物，对促肾上腺皮质激素释放因子过表达(CRF-OE)小鼠脱发的治疗作用。它也已用作某项检测的阳性对照，用于培养大鼠触须毛囊。 Minoxidil sulfate is a K|+|channel agonist and a strong vascular smooth muscle relaxant. It has been shown to relax norepinephrine contraction, and is reported to be a vasodilator. Minoxidil sulfate has been used to better understand the blood-brain tumor barrier in syngeneic and allogeneic rat studies and has demonstrated to increase tumor permeability.
