compound introduction
西拉普利是一种单乙酯，可作为血管紧张素转化酶（ACE）抑制剂。该抑制剂通过抑制ACE裂解血管紧张素I和Hip-His-Leu的键的功能发挥作用。已知西拉普利的二酸形式在抑制ACE方面比依那普利更有效。已知西拉普利被非特异性酯酶水解成其活性酸代谢物西拉普利拉。 产品应用： 西拉普利是一种血管紧张素转换酶 (ACE) 抑制剂，用于治疗高血压和充血性心力衰竭的药物的研究。 Cilazapril is a monoethyl ester, which acts as an angiotensin-converting enzyme (ACE) inhibitor. The inhibitor functions by inhibiting the the ability of ACE to cleave bonds of angiotensin I and Hip-His-Leu. It is known that the diacid form of Cilazapril is more potent that enalapril at inhibiting ACE. It is known that Cilazapril is hydrolyzed to its active acid metabolite, Cilazaprilat by non-specific esterases.
