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2-Cyanoethyl N,N-diisopropylchlorophosphoramidite

Dangerous Goods

CAS number：89992-70-1    molecular formula：C9H18ClN2OP

overview
Specs
numbering system
physicochemical properties
Safety information
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overview

compound introduction

用于可扩展性液相寡核苷酸合成，该合成用于亚磷酰胺化学和 DMT-、iBu- 以及 Bz-保护单体。中间体可通过萃取分离，无需进一步纯化。 用于寡脱氧核糖核苷酸合成过程中 3′-羟基的磷化试剂。 Phosphitylating reagent for -hydroxyl groups for use in the synthesis of oligodeoxyribonucleotides. Used in a scalable, solution-phase oligonucleotide synthesis employing phosphoramidite chemistry and DMT-, iBu- and Bz-protected monomers. Intermediates were isolated by extraction without further purification.

Specs

Chinese alias2-氰基乙基 二异丙基氯代亚磷酰胺
English alias3-[chloro-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile | cyanoethyl n,n-diisopropyl phosphoamidochloridite
CAS number89992-70-1molecular formulaC9H18ClN2OP
molecular weight236.68 g/molExact mass≥95%
PSA36.300 Ųlogp2.300

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram：
GHS05 , GHS02
Signal word：
Danger
Hazard Statement：
H314: 造成严重的皮肤灼伤和眼睛损伤 H250: 暴露在空气中会自燃
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P370+P378: 火灾时：使用干砂、干粉或抗醇泡沫灭火。 P210: 远离热源，热表面，火花，明火和其他点火源。 - 禁止抽烟。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P233: 保持容器密闭。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P222: 不允许接触空气 P231: 在惰性气体下处理 P301+P330+P331:
WGK Germany：
3
Personal protective equipment：
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Production methods and uses

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MSDS

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