DMT-dT Phosphoramidite belongs to the class of DNA Phosphoramidites.The key features of standard protected DNA phosphoramidite are: Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib)) Recommended cleavage and deprotection conditions are 8 hours at 55 °C or 24 hours at room temperature using concentrated ammonia solution for standard base-protected oligonucleotides The high coupling efficiency of Proligo′s DNA phosphoramidites leads to high-yield and high-quality oligonucleotides (a)
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DMT-dT Phosphoramidite
Dangerous GoodsCAS number:98796-51-1 molecular formula:C40H49N4O8P
overview
compound introduction
Specs
| Chinese alias | 5'-O-(4,4'-二甲氧基三苯甲基)-2'-脱氧胸苷-3'-O-[O-(2-氰基乙基)-N,N'-二异丙基亚] | 5'-O-[双(4-甲氧基苯基)苯基甲基]-2'-脱氧胸苷, 3'-[2-氰基乙基 N,N-双(1-甲基乙基)亚磷酰胺] | DMT-dT酰胺, 胸苷, 5'-O-[双(4-甲氧基苯基)苯基甲基]-, 3'-[2-氰基乙基 N,N-双(1-甲基乙基)亚磷酰胺] | ||
| English alias | DMT-dT amidite | (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | DMT-dT Pharmadite(R) | 5'-O-[Bis(4-Methoxyphenyl)phenylmethyl] | ||
| CAS number | 98796-51-1 | molecular formula | C40H49N4O8P |
| molecular weight | 744.81 g/mol | Exact mass | ≥99% |
| PSA | 132.000 Ų | logp | 5.700 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H319: 引起严重眼睛刺激
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续:寻求医疗帮助。
WGK Germany:
3
Production methods and uses
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upstream information
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downstream information
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MSDS
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